That Block was Perfect- Why Didn’t it Take? Biological Reasons for Local Anesthetic Failure (1 Class A CE with 1 Pharm and 1 Pain)

It is not uncommon for CRNAs to encounter peripheral and neuraxial blocks that fail to provide adequate analgesic relief despite precise placement and evidence of satisfactory functioning. While external factors such as improperly stored medications or incorrect block placement are often blamed, patient factors such as genetic influences on local anesthetic action play a larger role in block failure than previously recognized. This session will provide an review of mechanisms of action of local anesthetics, discuss basics of how genetic variants affect protein function, and examine several common genetic variants that contribute to variability in patient response to regional anesthesia.

Class A credit can only be earned for participation in synchronous learning via live in-person or live webinar sessions. In-person attendees can only receive Class A credit for the sessions they attend live.

Due to CE guidelines, sessions which are recorded will not be available for viewing immediately following Congress.